Article
Genome-wide identification of regulatory elements in Sertoli cells.
Development (Cambridge, England) - 15 Feb 2017
Maatouk Danielle M, Natarajan Anirudh, Shibata Yoichiro, Song Lingyun, Crawford Gregory E, Ohler Uwe, Capel Blanche
Abstract excerpt
A current goal of molecular biology is to identify transcriptional networks that regulate cell differentiation. However, identifying functional gene regulatory elements has been challenging in the context of developing tissues where material is limited and cell types are mixed. To identify regulatory sites during sex determination, we subjected Sertoli cells from mouse fetal testes to DNaseI-seq and ChIP-seq for...
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