Article

A Synthesis-Based Reverse Metabolomics Approach for the Discovery of Chemical Structures from Humans and Animals.

2021-08-30

Abstract excerpt

<title>Abstract</title> <p>Identification of metabolites in humans remains challenging. Here, we present synthesis-based reverse metabolomics as a strategy for structure elucidation that aims to also find phenotypic associations. In this approach, MS/MS spectra are acquired from newly synthesized compounds, and searched against public metabolomics data to uncover their phenotypic associations. To demonstrate the...

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Literature Corpus work: 6e0e0b99-2030-5957-8726-ca12f55c0b91
DOI: 10.21203/rs.3.rs-820302/v1

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