Article

Behavioral and genetic markers of susceptibility to escalate fentanyl intake

2024-12-12

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> The “loss of control” over drug consumption, present in opioid use disorder (OUD) and known as escalation of intake, is well-established in preclinical rodent models. However, little is known about how antecedent behavioral characteristics, such as valuation of hedonic reinforcers prior to drug use, may impact the trajectory of fentanyl intake over time. Moreover, it is uncl...

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Literature Corpus work: 17aa36d0-39b6-57a0-b864-c957ca75e5c8
DOI: 10.1101/2024.12.06.627259

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