Article

A spatial transcriptomics atlas of live donors reveals unique zonation patterns in the healthy human liver

2025-02-23

Abstract excerpt

Reconstructing gene expression atlases for human tissues is challenging due to limited access to healthy samples from live donors. Neurologically deceased donors often show ischemic changes, while tissues near diseased regions may have altered gene expression. The liver, with its unique regenerative capacity, allows analysis from live healthy donors (LHDs). Using spatial transcriptomics (Visum, Visium HD and MERFI...

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Literature Corpus work: 178fd38b-71f6-5c96-95d2-cc96b409bf21
DOI: 10.1101/2025.02.22.639181

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