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Single-cell RNA sequencing of human liver reveals hepatic stellate cell heterogeneity

21 Mar 2021

Abstract excerpt

Background & Aims The multiple vital functions of the human liver are performed by highly specialised parenchymal and non-parenchymal cells organised in complex collaborative sinusoidal units. Although crucial for homeostasis, the cellular make-up of the human liver remains to be fully elucidated. Here, single-cell RNA-sequencing was used to unravel the heterogeneity of human liver cells, in particular of...

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PMID: 34027339
DOI: 10.1016/j.jhepr.2021.100278

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