Article
Dual targeting of MAPK and PI3K pathways unlocks redifferentiation of <i>Braf</i> -mutated thyroid cancer organoids
2023-04-02
Abstract excerpt
Thyroid cancer is the most common endocrine malignancy and several genetic events have been described to promote the development of thyroid carcinogenesis. Besides the effects of specific mutations on thyroid cancer development, the molecular mechanisms controlling tumorigenesis, tumor behavior, and drug resistance are still largely unknown. Cancer organoids have been proposed as a powerful tool to study aspects r...
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Identifiers and source
- Literature Corpus work
- 1783d66b-eec1-5f9c-b259-b373788f3ff3
- DOI
- 10.1101/2023.03.30.534915