Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

This is Your Thyroid on Drugs: Targetable Mutations and Fusions in Thyroid Carcinoma.

Surgical pathology clinics - 1 Mar 2023

Chu Ying-Hsia

Abstract excerpt

This review aims to provide an overview of the molecular pathogenesis thyroid carcinomas, emphasizing genetic alterations that are therapeutically actionable. The main pathways in thyroid carcinogenesis are the MAPK and PI3K pathways. Point mutations and gene rearrangements affecting the pathway effectors and receptor tyrosine kinases are well-known drivers of thyroid cancer. Research over the past few decades...

Topics

Join the communities discussing this publication.

Mutation
Phosphatidylinositol 3-Kinases
Proto-Oncogene Proteins B-raf
Receptor Protein-Tyrosine Kinases
Thyroid Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36739167
DOI: 10.1016/j.path.2022.09.007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

This is Your Thyroid on Drugs: Targetable Mutations and Fusions in Thyroid Carcinoma.PMID 36739167Read ↗

This is Your Thyroid on Drugs: Targetable Mutations and Fusions in Thyroid Carcinoma.Semantic proximity Read ↗

The Role of the Kinase Inhibitors in Thyroid CancersSemantic proximity Read ↗

Targeted therapy in thyroid cancer: molecular alterations and clinical management.Semantic proximity Read ↗

Genomic alterations in thyroid cancer: biological and clinical insights.Semantic proximity Read ↗

Key signaling pathways in thyroid cancerSemantic proximity Read ↗

New Therapies for Advanced Thyroid Cancer.Semantic proximity Read ↗

Progress in Treating Advanced Thyroid Cancers in the Era of Targeted Therapy.Semantic proximity Read ↗

Genetic alterations in anaplastic thyroid carcinoma and targeted therapies (Review)Semantic proximity Read ↗

NOVEL INSIGHTS IN ADVANCED THYROID CARCINOMA: FROM MECHANISMS TO TREATMENTS: Molecular insights into the origin, biology, and treatment of anaplastic thyroid carcinoma.Semantic proximity Read ↗

Clinical and Translational Challenges in Thyroid Cancer.Semantic proximity Read ↗

Molecular genetics of thyroid cancer: implications for diagnosis, treatment and prognosisSemantic proximity Read ↗

Thyroid carcinoma: molecular pathways and therapeutic targetsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.