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NOVEL INSIGHTS IN ADVANCED THYROID CARCINOMA: FROM MECHANISMS TO TREATMENTS: Development of 3D organoid models to study aggressive thyroid cancers

20 Jun 2025

Abstract excerpt

Thyroid cancer (TC), particularly aggressive forms such as poorly differentiated thyroid carcinoma and anaplastic thyroid carcinoma, presents considerable clinical challenges due to limited treatment options and suboptimal outcomes. Organoid models, derived from patient samples or pluripotent stem cells (PSCs), offer a robust framework for elucidating the biology of these malignancies. Recent advancements in...

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PMID: 40540628
DOI: 10.1530/etj-24-0392

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