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This is Your Thyroid on Drugs: Targetable Mutations and Fusions in Thyroid Carcinoma.

Clinics in laboratory medicine - 1 Sept 2026

Chu Ying-Hsia

Abstract excerpt

This review aims to provide an overview of the molecular pathogenesis thyroid carcinomas, emphasizing genetic alterations that are therapeutically actionable. The main pathways in thyroid carcinogenesis are the MAPK and PI3K pathways. Point mutations and gene rearrangements affecting the pathway effectors and receptor tyrosine kinases are well-known drivers of thyroid cancer. Research over the past few decades...

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PMID: 42526969
DOI: 10.1016/j.cll.2026.06.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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