Article

Comparative validation of the BOADICEA and Tyrer-Cuzick breast cancer risk models incorporating classical risk factors and polygenic risk in a population-based prospective cohort

2020-05-04

Abstract excerpt

<h4>Purpose</h4> The Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation Algorithm (BOADICEA) and the Tyrer-Cuzick breast cancer models have recently been extended to include polygenic risk scores (PRS). In addition, BOADICEA has also been extended to include reproductive and lifestyle factors, which were already part of Tyrer-Cuzick model. We conducted a comparative validation of the extended...

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Literature Corpus work: 1780ef06-b87c-5d3b-a851-ddc5da1f9559
DOI: 10.1101/2020.04.27.20081265

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