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Article

Prospective validation of the BOADICEA multifactorial breast cancer risk prediction model in a large prospective cohort study.

Journal of medical genetics - 1 Dec 2022

Yang Xin, Eriksson Mikael, Czene Kamila, Lee Andrew, Leslie Goska, Lush Michael, Wang Jean, Dennis Joe, Dorling Leila, Carvalho Sara, Mavaddat Nasim, Simard Jacques, Schmidt Marjanka K, Easton Douglas F, Hall Per, Antoniou Antonis C

Abstract excerpt

BACKGROUND: The multifactorial Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation Algorithm (BOADICEA) breast cancer risk prediction model has been recently extended to consider all established breast cancer risk factors. We assessed the clinical validity of the model in a large independent prospective cohort. METHODS: We validated BOADICEA (V.6) in the Swedish KARolinska Mammography Project...

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Identifiers

PMID: 36162852
DOI: 10.1136/jmg-2022-108806
PMCID: PMC9691822

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