Article

Comparative Network Reconstruction using Mixed Integer Programming

2018-01-05

Abstract excerpt

New anti-cancer drugs that specifically target oncogenes involved in signalling show great clinical promise. However, the effectiveness of such targeted treatments is often hampered by innate or acquired resistance due to feedbacks, crosstalks or network adaptations in response to drug treatment. Addressing this problem requires an understanding of these networks and how they differ between cells with different on...

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Identifiers and source

Literature Corpus work: 176cbd58-b080-5430-916d-c338675ff97a
DOI: 10.1101/243709

Open publication

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