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Article

Quantitative evaluation and reversion analysis of the attractor landscapes of an intracellular regulatory network for colorectal cancer.

BMC systems biology - 5 Apr 2017

Kim Yunseong, Choi Sea, Shin Dongkwan, Cho Kwang-Hyun

Abstract excerpt

BACKGROUND: Cancer reversion, converting the phenotypes of a cancer cell into those of a normal cell, has been sporadically observed throughout history. However, no systematic analysis has been attempted so far. RESULTS: To investigate this from a systems biological perspective, we have constructed a logical network model of colorectal tumorigenesis by integrating key regulatory molecules and their interactions...

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Identifiers

PMID: 28381275
DOI: 10.1186/s12918-017-0424-2
PMCID: PMC5382366

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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