Article
Edge-based sensitivity analysis of signaling networks by using Boolean dynamics.
Bioinformatics (Oxford, England) - 1 Sept 2016
Trinh Hung-Cuong, Kwon Yung-Keun
Abstract excerpt
MOTIVATION: Biological networks are composed of molecular components and their interactions represented by nodes and edges, respectively, in a graph model. Based on this model, there were many studies with respect to effects of node-based mutations on the network dynamics, whereas little attention was paid to edgetic mutations so far. RESULTS: In this paper, we defined an edgetic sensitivity measure that...
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