Article

Alternative splicing in mechanically stretched podocytes as a model of glomerular hypertension

2024-07-19

Abstract excerpt

<h4>Background</h4> Alterations in pre-mRNA splicing play an important role in disease pathophysiology. However, the role of alternative splicing (AS) for podocytes in hypertensive nephropathy (HN) has not been investigated. The purpose of the Sys_CARE project was to identify AS events that play a role in the development and progression of HN. <h4>Methods</h4> Murine podocytes were exposed to mechanical stretch,...

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Literature Corpus work: 176343e2-1af5-59f0-a917-1ca0c0bec50c
DOI: 10.1101/2024.07.17.603550

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