Article

RNA Alternative Splicing and Polyadenylation and Regulation of the Glomerular Filtration Barrier

2024-09-26

Abstract excerpt

<h4>Background: </h4> Glomerular disease, characterized by podocyte injury and proteinuria, can lead to chronic kidney disease and end stage kidney disease. We hypothesized that the glomerular pathophysiology is associated with mRNA alternative splicing and polyadenylation of glomerular genes and of critical podocyte and slit diaphragm components that regulate the filtration barrier. <h4>Methods:</h4> Glomerular d...

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Literature Corpus work: 3279bf05-fe32-57c0-91ef-9a30267dd535
DOI: 10.1101/2024.09.26.615280

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