Article

Human Papillomavirus Genomes Associate with Active Host Chromatin during Persistent Viral Infection

2025-04-17

Abstract excerpt

<h4>ABSTRACT</h4> Human papillomaviruses (HPVs) maintain their genomes as minichromosomes in the nuclei of infected keratinocytes. This study investigates the association of HPV31 genomes with host chromatin using both HiC and 4C-seq chromosome conformation capture techniques. We show that HPV31 genomes preferentially associate with transcriptionally active A compartments of host chromatin, regions of open chroma...

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Literature Corpus work: 174200f2-2e1a-532d-adf8-eff691485f50
DOI: 10.1101/2025.04.15.649012

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