Article

Regulatory T Cell Function in Established Systemic Autoimmune Inflammation: Reversal and Containment of a Fatal Disease

2021-02-05

Abstract excerpt

<title>Abstract</title> <p>The immunosuppressive function of regulatory T (Treg) cells is dependent on continuous expression of the transcription factor Foxp3. Foxp3 loss-of-function or induced ablation of Treg cells results in a fatal autoimmune disease featuring all known types of inflammatory responses with every manifestation stemming from Treg cell paucity, highlighting a vital function of Treg cells in prev...

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Literature Corpus work: 16fcb9b7-8e8d-55eb-9bd0-b972afec4caa
DOI: 10.21203/rs.3.rs-153417/v1

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