Article
Regulatory T cells in human autoimmune diseases.
Springer seminars in immunopathology - 1 Aug 2006
Torgerson Troy R
Abstract excerpt
In the most simplistic terms, immune tolerance can be envisioned as a balance with autoreactive cells that arise naturally in all individuals on one side and regulatory mechanisms designed to counter those autoreactive processes on the other. A tilt of the balance toward the autoreactive side, either by increasing the number or function of autoreactive cells or by diminishing regulatory mechanisms, is manifested...
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