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Article

Function and Role of Regulatory T Cells in Rheumatoid Arthritis.

Frontiers in immunology - 1 Jan 2021

Jiang Qi, Yang Guocan, Liu Qi, Wang Shengjun, Cui Dawei

Abstract excerpt

Rheumatoid arthritis (RA) is a systemic and heterogeneous autoimmune disease with symmetrical polyarthritis as its critical clinical manifestation. The basic cause of autoimmune diseases is the loss of tolerance to self or harmless antigens. The loss or functional deficiency of key immune cells, regulatory T (Treg) cells, has been confirmed in human autoimmune diseases. The pathogenesis of RA is complex, and the...

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Identifiers

PMID: 33868244
DOI: 10.3389/fimmu.2021.626193
PMCID: PMC8047316

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