Article

Molecular Determinants of the Immunomodulatory Potentials of a Novel Bifunctional TGF-β1/PD-L1 Fusion Protein

2025-08-31

Abstract excerpt

<title>Abstract</title> <p>Purpose Autoimmune diseases (AIDs) are inflammatory conditions characterized by dysregulated immune tolerance. Conventional immunosuppressive therapies for AIDs may reduce overall immune activity, which pose risks of infection and malignancy. Transforming growth actor-beta 1 (TGF-β1) and programmed death-ligand 1 (PD-L1) are two immunoregulatory proteins known to independently modulate...

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Literature Corpus work: 16c6ae0d-809a-554a-80fa-533c232e81b5
DOI: 10.21203/rs.3.rs-7226263/v1

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