Article

An autologous cell-based therapeutic vaccine expressing IL6/1 fusokine drives robust anti-tumor response against ovarian cancer

2026-05-08

Abstract excerpt

<h4>Background</h4> Cytokines are immunomodulatory proteins that play central roles in regulating immune responses and represent attractive targets for cancer therapy. However, as single agents, cytokines have shown limited clinical benefit due to systemic toxicities and a short in vivo half-life. Our group has focused on engineering fusion cytokines (fusokines) that couple two cytokines into a single biologic to...

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Literature Corpus work: 62973aeb-6df3-5d31-90d7-e978a1a84003
DOI: 10.64898/2026.05.05.721149

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