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Engineered Bifunctional Proteins for Targeted Cancer Therapy: Prospects and Challenges

29 Sept 2021

Abstract excerpt

Bifunctional proteins (BFPs) are a class of therapeutic agents produced through genetic engineering and protein engineering, and are increasingly used to treat various human diseases, including cancer. These proteins usually have two or more biological functions-specifically recognizing different molecular targets to regulate the related signaling pathways, or mediating effector molecules/cells to kill tumor...

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PMID: 34585802
DOI: 10.1002/adma.202103114

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