Article

LRRC33 is a novel binding and regulating protein of TGF-β1 function in human acute myeloid leukemia cells

2019-02-25

Abstract excerpt

Transforming growth factor – β1 (TGF-β1) is a versatile cytokine. It has context-dependent pro- and anti-cell proliferation functions. Activation of latent TGF-β1 requires release of the growth factor from pro-complexes and is regulated through TGF-β binding proteins. Two types of TGF-β binding partners, latent TGF-β-binding proteins (LTBPs) and leucine-rich-repeat-containing protein 32 (LRRC32), have been identif...

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Literature Corpus work: 6598f69d-a94b-565b-b14c-77b869517339
DOI: 10.1101/560763

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