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Machine learning identifies cell-free DNA 5-hydroxymethylation biomarkers that detect occult colorectal cancer in PLCO Screening Trial subjects

2024-02-26

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Colorectal cancer (CRC) is a leading cause of cancer-related mortality, and CRC detection through screening improves survival rates. A promising avenue to improve patient screening compliance is the development of minimally-invasive liquid biopsy assays that target CRC biomarkers on circulating cell-free DNA (cfDNA) in peripheral plasma. In this report, we identify cfDNA bio...

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Literature Corpus work: 16b67077-cdf0-5344-a5f4-1e67b9f4d8a7
DOI: 10.1101/2024.02.25.581955

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