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Genome-wide discovery of circulating cell-free DNA methylation biomarkers for colorectal cancer detection

27 Jul 2023

Abstract excerpt

BACKGROUND: Colorectal polyp is known a precursor of colorectal cancer (CRC) that holds an increased risk for progression to CRC. Circulating cell-free DNA (cfDNA) methylation has shown favorable performance in the detection and monitoring the malignant progression in a variety of cancers. RESULTS: To discover cfDNA methylation markers for the diagnosis of CRC, we first performed a genome-wide analysis between...

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Cancer Genomics and Diagnostics
Colorectal Cancer Screening and Detection
Epigenetics and DNA Methylation

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37501075
DOI: 10.1186/s13148-023-01518-5

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