Article

Power and linkage disequilibrium differences are major confounders of human eQTL portability across ancestries and cohorts

2026-02-27

Abstract excerpt

The phenotypic effects of germline variants are often mediated through gene regulation. Expression quantitative trait loci (eQTLs) are genetic variants associated with changes in gene expression. Understanding how eQTLs vary across populations is essential for characterising the genetic and regulatory drivers of trait diversity. Meta-analysing eQTL studies from multiple populations enables more robust detection of...

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Literature Corpus work: 1684adce-f3c6-5ac9-b26f-f92a9c2c80d1
DOI: 10.64898/2026.02.26.708346

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