Article

On the cross-population generalizability of gene expression prediction models

2019-03-05

Abstract excerpt

The genetic control of gene expression is a core component of human physiology. For the past several years, transcriptome-wide association studies have leveraged large datasets of linked genotype and RNA sequencing information to create a powerful gene-based test of association that has been used in dozens of studies. While numerous discoveries have been made, the populations in the training data are overwhelmingl...

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Literature Corpus work: 1794166d-60d0-5658-8776-bde29409ef0a
DOI: 10.1101/552042

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