Article
Patterns of cis regulatory variation in diverse human populations.
PLoS genetics - 1 Jan 2012
Stranger Barbara E, Montgomery Stephen B, Dimas Antigone S, Parts Leopold, Stegle Oliver, Ingle Catherine E, Sekowska Magda, Smith George Davey, Evans David, Gutierrez-Arcelus Maria, Price Alkes, Raj Towfique, Nisbett James, Nica Alexandra C, Beazley Claude, Durbin Richard, Deloukas Panos, Dermitzakis Emmanouil T
Abstract excerpt
The genetic basis of gene expression variation has long been studied with the aim to understand the landscape of regulatory variants, but also more recently to assist in the interpretation and elucidation of disease signals. To date, many studies have looked in specific tissues and population-based samples, but there has been limited assessment of the degree of inter-population variability in regulatory...
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