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Article

HCK maintains the self-renewal of leukaemia stem cells via CDK6 in AML

2021-02-12

Abstract excerpt

<h4>Background: </h4> Leukaemia stem cells (LSCs) are responsible for the initiation, maintenance, and recurrence of acute myeloid leukaemia (AML), an aggressive haematological malignancy associated with drug resistance and relapse. Identifying therapeutic LSC targets is critical to curing AML. <h4>Methods: </h4>: Bioinformatics databases were used to identify therapeutic LSC targets. The conditional knockout mice...

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Literature Corpus work
167bf136-e25a-55e4-9241-325e8fdd3ef2
DOI
10.21203/rs.3.rs-218642/v1
Open publication

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HCK maintains the self-renewal of leukaemia stem cells via CDK6 in AMLDOI 10.21203/rs.3.rs-218642/v1
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