Article

Co-occupancy analysis reveals novel transcriptional synergies for axon growth

2020-06-12

Abstract excerpt

Transcription factors (TFs) act as powerful levers to regulate neural physiology and can be targeted to improve cellular responses to injury or disease. Because TFs often depend on cooperative activity, a major challenge is to identify and deploy optimal sets. Here we developed a novel bioinformatics pipeline, centered on TF co-occupancy of regulatory DNA, and used it to predict factors that potentiate the effects...

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Literature Corpus work: 1657a995-c2ed-500a-9a2d-dcf80b787e3e
DOI: 10.1101/2020.06.12.146159

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