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Article

Hyperactivated Stat3 boosts axon regeneration in the CNS.

Experimental neurology - 1 Jun 2016

Mehta Saloni T, Luo Xueting, Park Kevin K, Bixby John L, Lemmon Vance P

Abstract excerpt

Axonal regeneration after spinal cord injury (SCI) is intrinsically and extrinsically inhibited by multiple factors. One major factor contributing to intrinsic regeneration failure is the inability of mature neurons in the central nervous system (CNS) to activate regeneration-associated transcription factors (TFs) post-injury. A prior study identified TFs overexpressed in neurons of the peripheral nervous system...

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Source

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Identifiers

PMID: 27060489
DOI: 10.1016/j.expneurol.2016.03.004
PMCID: PMC4888791

Genes

STAT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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