Back to search

Article

Refinement of a published gene-physical activity interaction impacting HDL-cholesterol: role of sex and lipoprotein subfractions

2024-01-24

Abstract excerpt

Large-scale gene-environment interaction (GxE) discovery efforts often involve compromises in the definition of outcomes and choice of covariates for the sake of data harmonization and statistical power. Consequently, refinement of exposures, covariates, outcomes, and population subsets may be helpful to establish often-elusive replication and evaluate potential clinical utility. Here, we used additional datasets,...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
163de7a6-8c7d-50c7-a2f7-d0c4a9d64e39
DOI
10.1101/2024.01.23.24301689
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Refinement of a published gene-physical activity interaction impacting HDL-cholesterol: role of sex and lipoprotein subfractionsDOI 10.1101/2024.01.23.24301689
Refinement of a Published Gene-Physical Activity Interaction Impacting HDL-Cholesterol: Role of Sex and Lipoprotein Subfractions.Semantic proximity
Lipoprotein profile and metabolic fine-mapping of genetic lipid risk lociSemantic proximity
A combined observational and Mendelian randomization investigation reveals NMR-measured analytes to be risk factors of major cardiovascular diseasesSemantic proximity
High Density Lipoprotein pathway as a therapeutic target for coronary heart disease: individual participant meta-analysis in 28,597 individuals with 4197 coronary eventsSemantic proximity
Unraveling the Potential of Physical Activity and High-Intensity Interval Training in the Treatment of Familial Hypercholesterolemia: Impact on Cardiorespiratory Fitness, Atherosclerosis, and Underlying Mechanisms. Study protocol of the UPPA-FH ProjectSemantic proximity
Multiancestry Study of Gene-Lifestyle Interactions for Cardiovascular Traits in 610 475 Individuals From 124 Cohorts: Design and Rationale.Semantic proximity
Variance-quantitative trait loci enable systematic discovery of gene-environment interactions for cardiometabolic serum biomarkersSemantic proximity
Size-Resolved Lipoprotein Fatty Acid Content as a Novel Nuclear Magnetic Resonance-Derived Trait Specifically Associates with Genetic Variants That Control Fatty Acid Metabolism.Semantic proximity
Variance-quantitative trait loci enable systematic discovery of gene-environment interactions for cardiometabolic serum biomarkers.Semantic proximity
Genetic associations with lipoprotein subfractions provide information on their biological nature.Semantic proximity
Major lipids and lipoprotein levels and risk of blood pressure elevation: a Mendelian Randomisation studySemantic proximity
Whole-Genome Approach Discovers Novel Genetic and Nongenetic Variance Components Modulated by Lifestyle for Cardiovascular Health.Semantic proximity
Select a neighboring publication to make it the new centre.