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Article

Multiancestry Study of Gene-Lifestyle Interactions for Cardiovascular Traits in 610 475 Individuals From 124 Cohorts: Design and Rationale.

Circulation. Cardiovascular genetics - 1 Jun 2017

Rao D C, Sung Yun J, Winkler Thomas W, Schwander Karen, Borecki Ingrid, Cupples L Adrienne, Gauderman W James, Rice Kenneth, Munroe Patricia B, Psaty Bruce M

Abstract excerpt

BACKGROUND: Several consortia have pursued genome-wide association studies for identifying novel genetic loci for blood pressure, lipids, hypertension, etc. They demonstrated the power of collaborative research through meta-analysis of study-specific results. METHODS AND RESULTS: The Gene-Lifestyle Interactions Working Group was formed to facilitate the first large, concerted, multiancestry study to...

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Blood Pressure
Cohort Studies
Gene-Environment Interaction
Genome-Wide Association Study
Life Style

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PMID: 28620071
DOI: 10.1161/CIRCGENETICS.116.001649
PMCID: PMC5476223

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