Article

Investigating cellular dynamics and molecular pathways through single-cell RNA sequencing in an imiquimod-induced lupus-like model

2024-07-24

Abstract excerpt

<title>Abstract</title> <p>Background Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterized by extensive immune cell dysregulation. The use of Imiquimod (IMQ), a topical immune response modifier, in animal models generates lupus-like symptoms, providing a valuable platform for probing the disease's mechanisms. Methods This study utilized single-cell RNA sequencing (scRNA-seq) to chara...

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Literature Corpus work: 534d259d-dc00-5d15-a8da-abbdba52c067
DOI: 10.21203/rs.3.rs-4651888/v1

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