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Spatio-temporal interaction of immune and renal cells determines glomerular crescent formation in autoimmune kidney disease

2024-12-21

Abstract excerpt

Rapidly progressive glomerulonephritis (RPGN) is the most aggressive group of autoimmune kidney disease with the worst prognosis. Anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis, anti-glomerular basement membrane (anti-GBM) and lupus nephritis are the most common causes of RPGN and are characterized by the formation of glomerular crescents and infiltration of leukocytes that eventually lead to gl...

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Literature Corpus work
818a1b76-eaa6-5b74-9729-f1e48b4fcfe2
DOI
10.1101/2024.12.18.629206
Open publication

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Spatio-temporal interaction of immune and renal cells determines glomerular crescent formation in autoimmune kidney diseaseDOI 10.1101/2024.12.18.629206
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