Article

Immune and molecular landscape behind non-response to Mycophenolate Mofetil and Azathioprine in lupus nephritis therapy

2024-01-12

Abstract excerpt

<title>Abstract</title> <p>Lupus nephritis (LN) represents one of the most severe complications of systemic lupus erythematosus, leading to end-stage kidney disease in worst cases. Current first-line therapies for LN, including mycophenolate mofetil (MMF) and azathioprine (AZA), fail to induce long-term remission in 60–70% of the patients, evidencing the urgent need to delve into the molecular knowledge-gap behin...

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Literature Corpus work: 1376d9cc-7e78-5473-9b90-0b4ea33bb661
DOI: 10.21203/rs.3.rs-3783877/v1

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