Article
Genome-wide discovery for diabetes-dependent triglycerides-associated loci.
PloS one - 1 Jan 2022
Selvaraj Margaret Sunitha, Paruchuri Kaavya, Haidermota Sara, Bernardo Rachel, Rich Stephen S, Peloso Gina M, Natarajan Pradeep
Abstract excerpt
PURPOSE: We aimed to discover loci associated with triglyceride (TG) levels in the context of type 2 diabetes (T2D). We conducted a genome-wide association study (GWAS) in 424,120 genotyped participants of the UK Biobank (UKB) with T2D status and TG levels. METHODS: We stratified the cohort based on T2D status and conducted association analyses of TG levels for genetic variants with minor allele count (MAC) at...
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