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Article

Using Genetic Variants to Assess the Relationship Between Circulating Lipids and Type 2 Diabetes.

Diabetes - 1 Jul 2015

Fall Tove, Xie Weijia, Poon Wenny, Yaghootkar Hanieh, Mägi Reedik, Knowles Joshua W, Lyssenko Valeriya, Weedon Michael, Frayling Timothy M, Ingelsson Erik

Abstract excerpt

The effects of dyslipidemia on the risk of type 2 diabetes (T2D) and related traits are not clear. We used regression models and 140 lipid-associated genetic variants to estimate associations between circulating HDL cholesterol (HDL-C), LDL cholesterol (LDL-C), and triglycerides and T2D and related traits. Each genetic test was corrected for effects of variants on the other two lipid types and surrogates of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Source

Identifiers

PMID: 25948681
DOI: 10.2337/db14-1710

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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