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Article

The molecular genetic makeup of acute lymphoblastic leukemia

2012-12-08

Abstract excerpt

Abstract Genomic profiling has transformed our understanding of the genetic basis of acute lymphoblastic leukemia (ALL). Recent years have seen a shift from microarray analysis and candidate gene sequencing to next-generation sequencing. Together, these approaches have shown that many ALL subtypes are characterized by constellations of structural rearrangements, submicroscopic DNA copy number alterations, and sequ...

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Literature Corpus work
15a2fb3e-3ce4-533b-8361-7ea655df2d4a
DOI
10.1182/asheducation.v2012.1.389.3798360
Open publication

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The molecular genetic makeup of acute lymphoblastic leukemiaDOI 10.1182/asheducation.v2012.1.389.3798360
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