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Redefining ALL classification: toward detecting high-risk ALL and implementing precision medicine

21 May 2015

Abstract excerpt

Acute lymphoblastic leukemia (ALL) is the commonest childhood tumor and remains a leading cause of cancer death in the young. In the last decade, microarray and sequencing analysis of large ALL cohorts has revolutionized our understanding of the genetic basis of this disease. These studies have identified new ALL subtypes, each characterized by constellations of structural and sequence alterations that perturb...

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PMID: 25999453
DOI: 10.1182/blood-2015-02-580043

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