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Article

The molecular genetic makeup of acute lymphoblastic leukemia.

Hematology. American Society of Hematology. Education Program - 1 Jan 2012

Mullighan Charles G

Abstract excerpt

Genomic profiling has transformed our understanding of the genetic basis of acute lymphoblastic leukemia (ALL). Recent years have seen a shift from microarray analysis and candidate gene sequencing to next-generation sequencing. Together, these approaches have shown that many ALL subtypes are characterized by constellations of structural rearrangements, submicroscopic DNA copy number alterations, and sequence...

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Source

Identifiers

PMID: 23233609
DOI: 10.1182/asheducation-2012.1.389

Genes

JAK2
ABL1
CRLF2
ETV6
IKZF1
JAK1
PDGFRB
RUNX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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