Article

High-throughput measurements of neuronal activity in single human iPSC-derived glutamate neurons

2025-04-07

Abstract excerpt

Induced pluripotent stem cell (iPSC)-derived neurons provide a promising platform for studying neuronal function and modeling central nervous system (CNS) diseases. However, functional analysis of large populations of iPSC-derived neurons has been challenging. Here, we developed a high throughput strategy targeting N-methyl-D-aspartate receptors (NMDA-R) to enhance neuronal activity and reveal functional phenotype...

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Literature Corpus work: 1550a95e-9ae9-53b9-a076-6f49a4c6bb84
DOI: 10.1101/2025.04.07.646449

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