Article

Automated high-throughput patch clamp electrophysiology of hiPSC-derived neuronal models

2025-05-15

Abstract excerpt

<h4>ABSTRACT</h4> The advent of human induced pluripotent stem cells (hiPSCs) and their differentiation into neurons and brain organoids has revolutionized our ability to model brain disorders in a human context. However, current technologies to assay the electrophysiological properties of human neurons in these models remain limited by throughput, as single-cell manual patch clamp is laborious and resource inten...

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Literature Corpus work: 2528f2d0-1ee8-5a28-bffb-9f869cd77916
DOI: 10.1101/2025.05.12.653142

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