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Article

The MPO-463G>A polymorphism and lung cancer risk: a meta-analysis based on 22 case-control studies.

PloS one - 1 Jan 2013

Yang Jun-Ping, Wang Wen-Bo, Yang Xiao-Xi, Yang Lei, Ren Li, Zhou Fu-Xiang, Hu Liu, He Wei, Li Bai-Yu, Zhu Yan, Jiang Huan-Gang, Zhou Yun-Feng

Abstract excerpt

BACKGROUND: Myeloperoxidase (MPO) is an endogenous oxidant enzyme that produces reactive oxygen species (ROS) and may be involved in lung carcinogenesis. The MPO-463G>A polymorphism influences MPO transcription and has been associated with lung cancer susceptibility. However, the association between the MPO-463G>A polymorphism and lung cancer risk remains controversial. METHOD: To investigate the effect of this...

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Source

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Identifiers

PMID: 23840365
DOI: 10.1371/journal.pone.0065778
PMCID: PMC3688689

Genes

MPO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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