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Article

Myeloperoxidase: new polymorphisms and relation with lung cancer risk.

1 Dec 2003

Abstract excerpt

Myeloperoxidase (MPO) is an haemoprotein that metabolizes tobacco smoke procarcinogens such as benzo(a)pyrene and aromatic amines into highly reactive intermediates. A polymorphism in the MPO promoter (-463G>A), resulting in lower expression, was previously associated with a decrease in lung cancer risk. In this study, the MPO gene was analysed for new polymorphisms by denaturing high-performance liquid...

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PMID: 14646692
DOI: 10.1097/01.fpc.0000054143.14659.ba

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Myeloperoxidase: new polymorphisms and relation with lung cancer risk.PMID 14646692Read ↗

MyeloperoxidaseSemantic proximity Read ↗

Point: myeloperoxidase -463G --> a polymorphism and lung cancer risk.Semantic proximity Read ↗

Association between myeloperoxidase G-463A polymorphism and lung cancer risk.Semantic proximity Read ↗

The MPO-463G>A polymorphism and lung cancer risk: a meta-analysis based on 22 case-control studies.Semantic proximity Read ↗

Myeloperoxidase G463A polymorphism and risk of lung cancer.Semantic proximity Read ↗

Myeloperoxidase -463G>A polymorphism and risk of primary lung cancer in a Korean population.Semantic proximity Read ↗

Genetic polymorphism in myeloperoxidase but not GSTM1 is associated with risk of lung squamous cell carcinoma in a Chinese population.Semantic proximity Read ↗

Counterpoint: the myeloperoxidase -463G-->a polymorphism does not decrease lung cancer susceptibility in Caucasians.Semantic proximity Read ↗

Myeloperoxidase -463 G/A polymorphism is associated with lung cancer risk: A meta-analysis with 7420 cases and 9132 controls.Semantic proximity Read ↗

Myeloperoxidase (MPO) genotype and lung cancer histologic types: the MPO -463 A allele is associated with reduced risk for small cell lung cancer in smokers.Semantic proximity Read ↗

Association between MPO 463G>A polymorphism and risk of lung cancer: a meta-analysis.Semantic proximity Read ↗

Myeloperoxidase -463 (G-->A) polymorphism associated with lower risk of lung cancer.Semantic proximity Read ↗

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