Article

DeepDynamics resolves cell-subtype and clinicopathological dynamics from bulk RNA-seq to identify mediators of Alzheimer’s disease risk

2025-12-17

Abstract excerpt

Processes such as Alzheimer’s disease and aging are shaped by dynamic cascades of cellular and molecular changes. Mapping how genetic and environmental risk factors alter these cascades is critical for pinpointing disease susceptibility and guiding therapeutic intervention, yet this task requires dense sampling of cell-subtype and -subpopulation changes throughout the full course of disease. Bulk measurements prov...

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Literature Corpus work: 14bdc1b7-8bdd-5ed0-ab0e-d4beae80b161
DOI: 10.64898/2025.12.15.694345

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