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Article

Amyloid-beta peptides trigger premature functional and gene expression alterations in human-induced neurons

2023-07-06

Abstract excerpt

<title>Abstract</title> <p>Background Alzheimer’s disease (AD) is the most prevalent cause of dementia in the elderly, characterized by the presence of amyloid beta (Aβ) plaques, neurofibrillary tangles, neuroinflammation, synapse loss and neurodegeneration in the brain. The amyloid cascade hypothesis postulates that deposition of Aβ peptides is the causative agent of AD pathology, but we still lack comprehensiv...

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Literature Corpus work
148f9052-1cbb-5ece-a528-9eb973b12d90
DOI
10.21203/rs.3.rs-3138106/v1
Open publication

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Amyloid-beta peptides trigger premature functional and gene expression alterations in human-induced neuronsDOI 10.21203/rs.3.rs-3138106/v1
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