Article

Boosting The Peripheral Immune Response in the Skeletal Muscles Improved Motor Function in ALS Transgenic Mice

2021-10-13

Abstract excerpt

<title>Abstract</title> <p><bold><underline>Background:</underline></bold> Monocyte chemoattractant protein 1 (MCP1/CCL2) is one of the most powerful pro-inflammatory chemokines. However, its signalling is pivotal in driving axonal and muscle regeneration following injury. We previously showed that MCP1 is strongly upregulated in the nervous system of slow-progressing than fast-progressing SOD1<sup>G93A</sup> mic...

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Literature Corpus work: 146b48c2-391a-526c-971f-daf54d7d85cc
DOI: 10.21203/rs.3.rs-929588/v1

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