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Article

Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice.

Proceedings of the National Academy of Sciences of the United States of America - 8 Dec 2009

Chiu Isaac M, Phatnani Hemali, Kuligowski Michael, Tapia Juan C, Carrasco Monica A, Zhang Ming, Maniatis Tom, Carroll Michael C

Abstract excerpt

During injury to the nervous system, innate immune cells mediate phagocytosis of debris, cytokine production, and axon regeneration. In the neuro-degenerative disease amyotrophic lateral sclerosis (ALS), innate immune cells in the CNS are activated. However, the role of innate immunity in the per...

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Identifiers

PMID: 19933335
DOI: 10.1073/pnas.0911405106
PMCID: PMC2791631

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SOD1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19933335-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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